Topic 6 — Who to Refer & How: A Simple Workflow

“Advancing Melanoma Care: Early Identification, Timely Action, and Next-Generation Therapy,” is an educational video series focusing on earlier identification of advanced melanoma, routine HLA-A*02:01 testing, and timely referral to IMA203 (anzu-cel) trial sites. In Topic 6, “Who to Refer & How: A Simple Workflow,” Alison Betof, MD, PhD, FASCO—Director, Melanoma Program, Mark and Mary Stevens Endowed Scholar in Melanoma, and Director, Solid Tumor Cellular Therapy at Stanford University School of Medicine—provides information on how to identify eligible patients for the actively enrolling pivotal Phase 3 clinical trial evaluating anzu-cel, a PRAME-directed engineered TCR-T therapy. Topics in this brief educational video include key candidates for the trial, HLA testing, and referral workflow. The discussion concludes by highlighting the importance of timely trial enrollment and how early referral preserves performance status and T-cell fitness.